Presence of two genes in the body increasing the risk of having Dengue
The mechanism for the spread for the Dengue is quite similar when they are compared with the spread of malaria. Hence, finding the different modules which will cause the spread of Dengue is one of the major concerns for many researchers in the world. There are many ways through which the spread of Dengue can be treated. However, when it is coming to the defense of the body, there are also the other ways through which a person might become susceptible for having Dengue in such a short time.
According to the study that has been conducted in Wellcome Trust and the Agency for Science, Technology and Research, there are two types of genes variants that are present in the body which will increase the susceptibility for many people to the contraction of Dengue. There is also the racial exposure which also counts for it. Therefore, the people of South Asia and South East Asia are much more susceptible for having the Dengue, especially in the times of epidemic. The research has been published in the journal namely Nature Genetics. According to the researchers, there are more than 100 million cases that are being reported for Dengue. There are different serotypes for Dengue, and if the person has been vaccinated or immunized with one type, the contraction with the other serotype will waste all the efforts. One form of Dengue is hemorrhagic type, and hence, when the patients are suffering from this type, there will be reduced count of platelets in the body which will impair the coagulation of the blood, causing internal bleeds in the body and the finally the death of the patients.
According to the research done and then followed by the combination research done with the Oxford University Clinical Research unit, the investigation for the identification of these two genes has been one of the major concerns. Therefore, for the patients who are affected by the Dengue are being screened, and hence, among these, 2934 cases of Dengue are being checked for the presence of the two genes. The follow up scale was managed, and in the patients who are suffering from Dengue are reported to have the MICB on the chromosome 6 and another one namely PLCE1 was present on chromosome 10. Both of these genes are seen to be active in the patients who are being affected by Dengue.
